13 new genes found to cause world's biggest killer

Topdawg13 · Mar 7, 2011

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The discovery of 13 previously unknown gene variations and the confirmation of around 10 more should offer clues about how heart ailments such as coronary artery disease develop, and lead to new and more effective treatments, the researchers said.

The findings also suggest it may be worth mapping someone's profile of genetic variants for heart problems as part of routine clinical care in the future, with an eye to being able to offer more personalized prevention or treatment plans.

"With such information we should be able to better identify people at high risk early on in life and quickly take the steps to neutralize that excess risk," said Themistocles Assimes of Stanford University School of Medicine in the United States, one of many scientists across the world who worked on the study.

"Although we are inching closer to that day, we will probably need to reliably identify many more variants...over the next few years before it becomes useful to perform this genetic profiling in a doctor's office."

According to the World Health Organization (WHO), cardiovascular diseases are the world's largest killers, claiming 17.1 million lives a year. Billions of dollars are spent every year on medical devices and drugs to treat them.
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