I have pretty good depth at RB and WR and don't have a clue who to start. Should I throw AJ Green or Best into the starting lineup?

Also, if you were to trade 2 players from this roster to upgrade the RB position, who would it be? I'm just not sure of what moves to make if any...

QB: Cam Newton vs NO
RB: Ahmad Bradshaw vs SEA
RB: Ryan Mathews @ DEN
WR: Calvin Johnson vs CHI
WR: Greg Jennings @ ATL
WR: Dwayne Bowe @ IND
TE: Vernon Davis vs TB

BN: Eli Manning vs SEA
BN: Jahvid Best vs CHI
BN: Mark Ingram @ CAR
BN: Marques Colston @CAR
BN: AJ Green @ JAC
BN: Mike Williams @ SF