Something similar happened with Ronny Turiaf though they weren't too specific about what Mandeville's issue is. If it can be surgically repaired, he could still surprise in the pros.
Eddy Curry? I think he had Hypertrophic Cardiomyopathy, which I don't think is Mandeville's case if what's little out there on Mandeville's condition is true (heart valve abnormality).