U.S. baby's cure from HIV raises hope, new questions

4 replies

Frumundah FinnaticFrumundah FinnaticNew MemberOP
Mar 4, 2013, 11:04 PM

In a medical first for an infant, the Mississippi toddler was born in July 2010 infected with HIV, treated within 30 hours of delivery with aggressive HIV therapy, which continued for 18 months. She is now considered cured of her infection, a team of researchers led by Dr. Deborah Persaud, a virologist at Johns Hopkins University in Baltimore, said in a news conference at the Conference on Retroviruses and Opportunistic Infections in Atlanta on Sunday.

"From a clinical perspective, this means that if you can get an infected baby on to antiretroviral drugs immediately after delivery, it's going to be possible to prevent or reverse the infection - essentially cure the baby," said Dr. Steven Deeks, an HIV/AIDS researcher at the University of California at San Francisco who is attending the conference, where the case was presented to researchers on Monday.

Great news indeed.

MonstBlitz;2232016 wrote:

It wouldn't surprise me if he is retained. Jeff Ireland is the nightmare that won't end. The **** stain you cannot flush. The Herpes for which there is no cure.

SilverphinSilverphinforum_veteran
Mar 7, 2013, 08:35 AM

Is it possible that this type of therapy can be used on adults?

EshlemonEshlemonforum_veteran
Mar 19, 2013, 04:50 PM

"Silverphin wrote:

Is it possible that this type of therapy can be used on adults?

Don't know why adults can't be cured either, as for adults a release today on "a functional cure".

http://www.nytimes.com/2013/03/16/world/europe/french-study-indicates-some-patients-can-control-hiv-after-stopping-treatment.html

French Study Indicates Some Patients Can Control H.I.V. After Stopping Treatment
By ANDREW POLLACK and DONALD G. McNEIL Jr.
Published: March 15, 2013

French researchers have identified 14 adults who have been able to control their H.I.V. infection for years after stopping treatment with antiviral drugs, a finding that suggests that some patients might be able to achieve a so-called functional cure.

The report comes only two weeks after doctors in the United States announced that a baby born in Mississippi had apparently been cured of infection with the virus that causes AIDS.

In both cases, scientists said, a crucial element appears to be initiating drug treatment shortly after the infection occurs, though that is not always practical. In the case of the French patients, treatment began within several months of infection, faster than is the case for most adults.

Jimmy JamesJimmy JamesNew Member
Mar 19, 2013, 06:09 PM

The baby cure won't likely directly lead to an adult cure because evidently there are places in the body the virus can hide and lay dormant. They basically got to the baby's virus before it could colonize those areas. With that said, the principles at play if repeatable will very likely contribute to a body of understanding just like the case of the so-called Berlin patient, the first man cured. If I remember his case right, he got a bone marrow transplant. A functional cure should happen within the decade easily as I understand it, and it is very possible even more promising things will happen as well.

Ohio FanaticOhio Fanaticsubscriber
Mar 25, 2013, 07:31 PM

"Jimmy James wrote:

The baby cure won't likely directly lead to an adult cure because evidently there are places in the body the virus can hide and lay dormant. They basically got to the baby's virus before it could colonize those areas. With that said, the principles at play if repeatable will very likely contribute to a body of understanding just like the case of the so-called Berlin patient, the first man cured. If I remember his case right, he got a bone marrow transplant. A functional cure should happen within the decade easily as I understand it, and it is very possible even more promising things will happen as well.

As someone who's spent years working on anti-viral research, including HIV, I don't think it will be that easy to achieve in 10 years. First, getting bone-marrow transplants for all the HIV patients is not feasible. It's difficult enough to get a match for one person. The reason why patients who are compliant with the full treatment cocktail of anti-virals are showing success is because the cocktails now contain multiple HIV drugs that all have very different mechanisms of action, making it much harder for the HIV virus to find a workaround either through mutation or adaption. But, viruses usually find a way to stay ahead of the curve. which is why is important for research companies to keep trying to find new HIV treatments to either shorten the duration of treatment or find a new target in the HIV viral life cycle.

testing

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